Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of... Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory symptoms requiring parenteral antibiotics, aerosolized human DNase I...
- Mechanism
- Curator reviewed
Pharmacologically active on DNA
- Also known as
- DNase I
What you can answer from here — as of September 16, 2026
Which companies are running trials of Deoxyribonuclease I, in which indications and phases, and which of those programs are still active?
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