NAV

Dialyzable leukocyte extract

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Dialyzable leukocyte extract
DrugBank Accession Number
DB16530
Background

Transferon is comprised of several peptides mixed from human dialyzable leucocyte extracts and acts as an immunomodulator. It is thought to have widespread effects on the immune system, and effective in treating infections and immunological issues.

Type
Biotech
Groups
Investigational
Synonyms
Not Available
External IDs
  • Dialyzable leukocyte extract
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. Hernandez-Esquivel MA, Perez-Torres A, Romero-Romero L, Reyes-Matute A, Loaiza B, Mellado-Sanchez G, Pavon L, Medina-Rivero E, Pestell RG, Perez-Tapia SM, Velasco-Velazquez MA: The dialyzable leukocyte extract Transferon(TM) inhibits tumor growth and brain metastasis in a murine model of prostate cancer. Biomed Pharmacother. 2018 May;101:938-944. doi: 10.1016/j.biopha.2018.03.012. Epub 2018 Mar 22. [Article]
  2. Mellado-Sanchez G, Lazaro-Rodriguez JJ, Avila S, Vallejo-Castillo L, Vazquez-Leyva S, Carballo-Uicab G, Velasco-Velazquez M, Medina-Rivero E, Pavon L, Chacon-Salinas R, Perez-Tapia SM: Development of Functional Antibodies Directed to Human Dialyzable Leukocyte Extract (Transferon(R)). J Immunol Res. 2019 May 16;2019:2754920. doi: 10.1155/2019/2754920. eCollection 2019. [Article]
  3. Wang JF, Park AJ, Rendini T, Levis WR: Lawrence Transfer Factor: Transference of Specific Immune Memory by Dialyzable Leukocyte Extract from a CD8+ T Cell Line. J Drugs Dermatol. 2017 Dec 1;16(12):1198-1206. [Article]
  4. Armides Franco-Molina M, Mendoza-Gamboa E, Castillo-Tello P, Tamez-Guerra RS, Villarreal-Trevino L, Tijerina-Menchaca R, Castillo-Leon L, Zapata-Benavides P, Rodriguez-Padilla C: In vitro antibacterial activity of bovine dialyzable leukocyte extract. Immunopharmacol Immunotoxicol. 2006;28(3):471-83. doi: 10.1080/08923970600928072. [Article]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Unknown StatusTreatmentCoronavirus Disease 2019 (COVID‑19)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at February 01, 2021 19:02 / Updated at February 13, 2021 10:54