Ethyl nitrite

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Ethyl nitrite is an ingredient in cough syrups for symptomatic treatment of cough, cold, bronchitis, and phlegm.

Generic Name
Ethyl nitrite
DrugBank Accession Number
DB16560
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 75.067
Monoisotopic: 75.032028405
Chemical Formula
C2H5NO2
Synonyms
  • Ethylester kyseliny dusite
  • Nitrous acid, ethyl ester
  • Nitrous ether spirit
  • Spirit of ethyl nitrite
External IDs
  • 203-722-6
  • FEMA NO. 2446

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ยาไอเด็กองุ่นEthyl nitrite (0.037 ml/5ml) + Ammonia (0.007 ml/5ml) + Glycyrrhiza glabra (0.17 ML/5ml) + Tolu balsam (0.22 ml/5ml)Syrupห้างหุ้นส่วนจำกัด ห้างขายยา กรุงเทพฯฟามาซี1983-08-30Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
8C7CJ279RV
CAS number
109-95-5
InChI Key
QQZWEECEMNQSTG-UHFFFAOYSA-N
InChI
InChI=1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
IUPAC Name
ethyl nitrite
SMILES
CCON=O

References

General References
  1. FDA Thailand: Baby Cough Syrup (Ammonia, Ethyl Nitrate, Glycyrrhiza glabra, Tolu Balsam) Oral Syrup [Link]
Human Metabolome Database
HMDB0031239
ChemSpider
7735
RxNav
1921585
ChEMBL
CHEMBL1551365
ZINC
ZINC000005650763
Wikipedia
Ethyl_nitrite

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Syrup
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility50.7 mg/mLALOGPS
logP0.42ALOGPS
logP0.9ChemAxon
logS-0.17ALOGPS
pKa (Strongest Basic)-2.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area38.66 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity17.95 m3·mol-1ChemAxon
Polarizability6.79 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on February 08, 2021 16:59 / Updated on May 22, 2021 06:02