Ethyl nitrite
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Ethyl nitrite is an ingredient in cough syrups for symptomatic treatment of cough, cold, bronchitis, and phlegm.
- Generic Name
- Ethyl nitrite
- DrugBank Accession Number
- DB16560
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 75.067
Monoisotopic: 75.032028405 - Chemical Formula
- C2H5NO2
- Synonyms
- Ethylester kyseliny dusite
- Nitrous acid, ethyl ester
- Nitrous ether spirit
- Spirit of ethyl nitrite
- External IDs
- 203-722-6
- FEMA NO. 2446
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Bronchitis Combination Product in combination with: Ammonia (DB11118), Tolu balsam (DB11223), Glycyrrhiza glabra (DB14312) •••••••••••• ••••• Used in combination for symptomatic treatment of Common cold Combination Product in combination with: Ammonia (DB11118), Tolu balsam (DB11223), Glycyrrhiza glabra (DB14312) •••••••••••• ••••• Used in combination for symptomatic treatment of Coughing Combination Product in combination with: Ammonia (DB11118), Tolu balsam (DB11223), Glycyrrhiza glabra (DB14312) •••••••••••• ••••• Used in combination for symptomatic treatment of Phlegm Combination Product in combination with: Glycyrrhiza glabra (DB14312), Ammonia (DB11118), Tolu balsam (DB11223) •••••••••••• ••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ยาไอเด็กองุ่น Ethyl nitrite (0.037 ml/5ml) + Ammonia (0.007 ml/5ml) + Glycyrrhiza glabra (0.17 ML/5ml) + Tolu balsam (0.22 ml/5ml) Syrup ห้างหุ้นส่วนจำกัด ห้างขายยา กรุงเทพฯฟามาซี 1983-08-30 Not applicable Thailand
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 8C7CJ279RV
- CAS number
- 109-95-5
- InChI Key
- QQZWEECEMNQSTG-UHFFFAOYSA-N
- InChI
- InChI=1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3
- IUPAC Name
- ethyl nitrite
- SMILES
- CCON=O
References
- General References
- FDA Thailand: Baby Cough Syrup (Ammonia, Ethyl Nitrate, Glycyrrhiza glabra, Tolu Balsam) Oral Syrup [Link]
- External Links
- Human Metabolome Database
- HMDB0031239
- ChemSpider
- 7735
- 1921585
- ChEMBL
- CHEMBL1551365
- ZINC
- ZINC000005650763
- Wikipedia
- Ethyl_nitrite
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Syrup - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 50.7 mg/mL ALOGPS logP 0.42 ALOGPS logP 0.9 Chemaxon logS -0.17 ALOGPS pKa (Strongest Basic) -2.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 38.66 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 17.95 m3·mol-1 Chemaxon Polarizability 6.79 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-004i-9000000000-ef50a1b26be87c8e4d08 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-00dj-9000000000-efcf4c1adfb6e2a9a2c7 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-004i-9000000000-ca4ae6c6b37fff990991 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0002-9000000000-eed213a3432071f20f67 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0002-9000000000-27c2f0e23cad145ef1a2 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0002-9000000000-4927c5cd56e2d96da9bf Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 103.2755112 predictedDarkChem Lite v0.1.0 [M-H]- 103.3675112 predictedDarkChem Lite v0.1.0 [M-H]- 117.80871 predictedDeepCCS 1.0 (2019) [M+H]+ 104.0989112 predictedDarkChem Lite v0.1.0 [M+H]+ 104.1786112 predictedDarkChem Lite v0.1.0 [M+H]+ 119.69617 predictedDeepCCS 1.0 (2019) [M+Na]+ 103.8215112 predictedDarkChem Lite v0.1.0 [M+Na]+ 127.31613 predictedDeepCCS 1.0 (2019)
Drug created at February 08, 2021 16:59 / Updated at May 22, 2021 06:02