Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Prevnar 20
Generic Name
Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
DrugBank Accession Number
DB16714
Background

Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Conjugate
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Prevnar 20Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularA-S Medication Solutions2021-08-10Not applicableUS flag
Prevnar 20Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen (4.4 ug/0.5mL) + Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL) + Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 ug/0.5mL)Injection, suspensionIntramuscularWyeth Pharmaceutical Division of Wyeth Holdings LLC2021-08-10Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
N47C1SHV0F
CAS number
Not Available

References

General References
Not Available
RxNav
2566291

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4RecruitingBasic ScienceCoronavirus Disease 2019 (COVID‑19) / Lymphoma1
3Active Not RecruitingPreventionMeningococcal Infections1
3Active Not RecruitingPreventionRespiratory Syncytial Virus (RSV) Infection1
3CompletedPreventionPneumococcal Infection1
2CompletedPreventionVaccines, Pneumococcal1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at August 19, 2021 20:38 / Updated at August 22, 2021 03:36