Tyrphostin B44

DB16762ExperimentalSmall molecule

Tyrphostin B44: Overview.

Mechanism: Pharmacologically active on Tyrosine-protein kinase SYK
Curator reviewed
Formula / weight: C₁₈H₁₆N₂O₃ · 308.337 g/mol (avg)
Also known as: AG 527 · AG527 · Tyrphostin AG 527 · Tyrphostin B-44 · Tyrphostin B44, (-) enantiomer

Resolves to

Compound

Structure

InChIKeyUMGQVUWXNOJOSJ-KMHUVPDISA-NSMILESC[C@@H](NC(=O)C(=C\C1=CC(O)=C(O)C=C1)\C#N)C1=CC=CC=C1

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Tyrphostin B44, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.