Influenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated)

Identification

Summary

Influenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) is a component of an inactivated influenza vaccine.

Brand Names
Fluzone High-Dose Quadrivalent, Fluzone Quadrivalent
Generic Name
Influenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated)
DrugBank Accession Number
DB16917
Background

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in an immunological defense against future exposure to the virus, or "antigen". This defense includes the production of humoral immunity through the development of antibodies and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. Inactivated viruses cannot replicate and thus cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Inactivated
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
FLUZONE High-Dose Quadrivalent Northern HemisphereInfluenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (60 ug/0.7mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2022-07-01Not applicableUS flag
Fluzone High-Dose Quadrivalent Northern HemisphereInfluenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza A Virus A/Victoria/4897/2022 IVR-238 (H1N1) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (60 ug/0.7mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2023-06-302024-06-30US flag
FLUZONE High-Dose Quadrivalent Southern HemisphereInfluenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) (60 ug/0.5mL) + Influenza A Virus A/Sydney/5/2021 SAN-013 (H1N1) antigen (formaldehyde inactivated) (60 ug/0.5mL) + Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated) (60 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (60 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2023-02-132023-12-31US flag
Fluzone Quadrivalent Northern HemisphereInfluenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2022-07-01Not applicableUS flag
Fluzone Quadrivalent Northern HemisphereInfluenza B virus B/Michigan/01/2021 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A Virus A/Victoria/4897/2022 IVR-238 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Darwin/9/2021 SAN-010 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2023-06-302024-06-30US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
Not Available
RxNav
2593400

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionIntramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at September 13, 2022 15:05 / Updated at December 01, 2022 11:32