Identification
- Summary
Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen is a component of a recombinant influenza vaccine comprising a recombinant influenza hemagglutinin antigen.
- Brand Names
- Flublok Quadrivalent
- Generic Name
- Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen
- DrugBank Accession Number
- DB16922
- Background
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in an immunological defense against future exposure to the virus, or "antigen". This defense includes the production of humoral immunity through the development of antibodies and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus.
There are three basic types of vaccines available: inactivated influenza vaccine (IIV), live attenuated influenza vaccine (LAIV), and recombinant influenza vaccines (RIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. Inactivated viruses cannot replicate and thus cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability. Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Recombinant - Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Flublok Quadrivalent Northern Hemisphere Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen (45 ug/0.5mL) + Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen (45 ug/0.5mL) Injection Intramuscular Sanofi Pasteur Inc. 2023-06-30 2024-06-30 US 
Flublok Quadrivalent Northern Hemisphere Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen (45 ug/0.5mL) Injection Intramuscular Sanofi Pasteur Inc. 2022-07-01 Not applicable US Flublok Trivalent Northern Hemisphere Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen (45 ug/0.5mL) + Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen (45 ug/0.5mL) Injection Intramuscular Sanofi Pasteur Inc. 2024-03-04 2024-06-30 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection Intramuscular - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at September 13, 2022 15:50 / Updated at December 01, 2022 11:32