ATH434

DB16965ApprovedInvestigationalSmall molecule

ATH434: Overview.

Mechanism: Pharmacologically active on Alpha-synuclein and Iron
Curator reviewed
Formula / weight: C₁₂H₁₃Cl₂N₃O₂ · 302.16 g/mol (avg)
Also known as: 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-one
Code names: ATH-434 · PBT-434

Resolves to

Compound

Structure

InChIKeyLQNHWKHRUWSYBK-UHFFFAOYSA-NSMILESCCNCC1=NC2=C(C(Cl)=CC(Cl)=C2O)C(=O)N1C

Targets

What you can answer from here — as of September 16, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with ATH434, and which of those have an active Phase 3 trial?

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