Sepantronium

DB17062InvestigationalSmall molecule

Sepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.

Chemical structure of Sepantronium
Mechanism
Curator reviewed
Formula / weight
C20H19N4O3 · 363.396 g/mol (avg)
Also known as
1h-naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)- · Sepantronium cation · Sepantronium ion

Resolves to

Compound
UNIIUZ77T1VFBMCAS753440-91-4ChEMBLCHEMBL2110734ChEBI94552
Structure
InChIKeyOTSOOHRUMBRSHZ-UHFFFAOYSA-NSMILESCOCC[N+]1=C(C)N(CC2=NC=CN=C2)C2=C1C(=O)C1=CC=CC=C1C2=O
Targets
Q12906ILF3Q93009USP7
Transporters
P08183ABCB1O15244SLC22A2O15245SLC22A1O75751SLC22A3Q8IXU6SLC35F2

What you can answer from here — as of September 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
5TransportersSubstrate / inhibitor direction, not just membership
Listed above
10Clinical trialsPhase, status and sponsor resolved per trial
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14+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sepantronium, and which of those have an active Phase 3 trial?

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