PF-4136309

DB17200InvestigationalSmall molecule

PF-4136309: Overview.

Mechanism: Pharmacologically active on C-C chemokine receptor type 2
Curator reviewed
Formula / weight: C₂₉H₃₁F₃N₆O₃ · 568.601 g/mol (avg)
Also known as: Benzamide, n-(2-((3s)-3-((trans-4-hydroxy-4-(5-(2-pyrimidinyl)- 2-pyridinyl)cyclohexyl)amino)-1-pyrrolidinyl)-2-oxoethyl)-3-(trifluoromethyl)- · N-(2-((3s)-3-((trans-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2- yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide
Code names: INCB-8761 · PF-04136309 · PF-4136309

Resolves to

Compound

Structure

InChIKeyZNSVOHSYDRPBGI-LXWOLXCRSA-NSMILES[H][C@@]1(CC[C@](O)(CC1)C1=CC=C(C=N1)C1=NC=CC=N1)N[C@H]1CCN(C1)C(=O)CNC(=O)C1=CC(=CC=C1)C(F)(F)F

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with PF-4136309, and which of those have an active Phase 3 trial?

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