Redaporfin
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Identification
- Generic Name
- Redaporfin
- DrugBank Accession Number
- DB17219
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 1135.11
Monoisotopic: 1134.156770216 - Chemical Formula
- C48H38F8N8O8S4
- Synonyms
- 3,3',3'',3'''-(7,8,17,18-tetrahydroporphyrin-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methylbenzenesulfonamide)
- Benzenesulfonamide, 3,3',3'',3'''-(7,8,17,18-tetrahydro-21h,23h-porphine-5,10,15,20-tetrayl)tetrakis(2,4-difluoro-n-methyl-
- Redaporfin
- External IDs
- F2BMET
- LUZ-11
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- ZP3QP1H44W
- CAS number
- 1224104-08-8
- InChI Key
- CKRVBMUJCFKRND-ZXWMLXKTSA-N
- InChI
- InChI=1S/C48H38F8N8O8S4/c1-57-73(65,66)33-17-5-21(49)37(45(33)53)41-25-9-11-27(61-25)42(38-22(50)6-18-34(46(38)54)74(67,68)58-2)29-13-15-31(63-29)44(40-24(52)8-20-36(48(40)56)76(71,72)60-4)32-16-14-30(64-32)43(28-12-10-26(41)62-28)39-23(51)7-19-35(47(39)55)75(69,70)59-3/h5-9,11,14,16-20,57-61,64H,10,12-13,15H2,1-4H3/b41-25+,41-26+,42-27+,42-29+,43-28+,43-30+,44-31+,44-32+
- IUPAC Name
- 2,4-difluoro-N-methyl-3-{7,12,17-tris[2,6-difluoro-3-(methylsulfamoyl)phenyl]-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3,5,7,11(23),12,14,16,18(21)-nonaen-2-yl}benzene-1-sulfonamide
- SMILES
- CNS(=O)(=O)C1=CC=C(F)C(=C1F)C1=C2\CCC(=N2)\C(=C2/N\C(\C=C2)=C(/C2=N/C(/CC2)=C(\C2=CC=C\1N2)C1=C(F)C(=CC=C1F)S(=O)(=O)NC)C1=C(F)C(=CC=C1F)S(=O)(=O)NC)\C1=C(F)C(=CC=C1F)S(=O)(=O)NC
References
- General References
- Not Available
- External Links
- ChemSpider
- 52085077
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1, 2 Unknown Status Treatment Head And Neck Cancer 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00178 mg/mL ALOGPS logP 4.4 ALOGPS logP 6.1 Chemaxon logS -5.8 ALOGPS pKa (Strongest Acidic) 7.64 Chemaxon pKa (Strongest Basic) 2.56 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 10 Chemaxon Hydrogen Donor Count 6 Chemaxon Polar Surface Area 242.04 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 263.78 m3·mol-1 Chemaxon Polarizability 107.24 Å3 Chemaxon Number of Rings 9 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 28, 2022 21:04 / Updated at December 01, 2022 11:36