DT2216

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DB18020InvestigationalSmall molecule

DT2216: Overview.

Mechanism: Pharmacologically active on Bcl-2-like protein 1
Curator reviewed
Formula / weight: C₇₇H₉₆ClF₃N₁₀O₁₀S₄ · 1542.36 g/mol (avg)
Code names: DT-2216

Resolves to

Compound

UNIIY8JQ9V7JAJCAS2365172-42-3ChEMBLCHEMBL4745523

Structure

InChIKeyPXVFFBGSTYQHRO-REQIQPEASA-NSMILES

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCC(=O)N1CCN(CC[C@H](CSC2=CC=CC=C2)NC2=CC=C(C=C2S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)C2=CC=C(C=C2)N2CCN(CC3=C(CCC(C)(C)C3)C3=CC=C(Cl)C=C3)CC2)CC1)C(C)(C)C)C1=CC=C(C=C1)C1=C(C)N=CS1

Targets

Q07817BCL2L1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with DT2216, and which of those have an active Phase 3 trial?

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