ZY19489

DB18062InvestigationalSmall molecule

ZY19489: Overview.

Mechanism: Pharmacologically active on Chloroquine resistance transporter
Curator reviewed
Formula / weight: C₂₄H₃₂FN₉ · 465.581 g/mol (avg)
Code names: MMV-253 · ZY-19489

Resolves to

Compound

Structure

InChIKeyHKPQFVAUXAZCDY-OAHLLOKOSA-NSMILESC[C@@H]1CN(CCN1C)C1=CN=C(NC2=CC(C3CC3)=C(F)C(C)=N2)N=C1NC1=NN(C)C(C)=C1

Targets

Transporters

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with ZY19489, and which of those have an active Phase 3 trial?

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