5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine

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DB18065InvestigationalSmall molecule

5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine: Overview.

Mechanism: Pharmacologically active on Chitotriosidase-1
Curator reviewed
Formula / weight: C₁₉H₂₇ClN₆O · 390.92 g/mol (avg)
Also known as: 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]- · 5-[4-[(2S,5S)-5-[(4-Chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine
Code names: GLP 4716 · GLPG4716 · OAT 889 · OATD-01

Resolves to

Compound

UNIIX4D0G881CNCAS2088453-21-6ChEMBLCHEMBL4788866

Structure

InChIKeySTWVLEKJQQRGMO-GUYCJALGSA-NSMILESC[C@H]1CN([C@@H](CC2=CC=C(Cl)C=C2)CO1)C1CCN(CC1)C1=NC(N)=NN1

Targets

Q13231CHIT1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine, and which of those have an active Phase 3 trial?

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