Nemvaleukin alfa
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Nemvaleukin alfa
- DrugBank Accession Number
- DB18187
- Background
Not Available
- Type
- Biotech
- Groups
- Investigational
- Biologic Classification
- Protein Based Therapies
Fusion proteins - Protein Chemical Formula
- Not Available
- Protein Average Weight
- Not Available
- Sequences
- Not Available
- Synonyms
- 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with 4-74-interleukin 2 (human) fusion protein with peptide linker (gsgggs) fusion protein with 1-165-interleukin 2 receptor .alpha.-chain (human)
- 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with 4-74-interleukin 2 (human) fusion protein with peptide linker (GSGGGS) fusion protein with 1-165-interleukin 2 receptor α-chain (human)
- Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha
- human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor α-chain fragment (139-303), produced in Ch
- External IDs
- ALKS 4230
- ALKS-4230
- ALKS4230
- RDB-1450
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Chemical TaxonomyProvided by Classyfire
- Description
- Not Available
- Kingdom
- Organic Compounds
- Super Class
- Organic Acids
- Class
- Carboxylic Acids and Derivatives
- Sub Class
- Amino Acids, Peptides, and Analogues
- Direct Parent
- Peptides
- Alternative Parents
- Not Available
- Substituents
- Not Available
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 7ZX1Q9SJ1F
- CAS number
- 2315268-27-8
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Active Not Recruiting Treatment Fallopian Tube Cancer / Platinum-resistant Ovarian Cancer / Primary Peritoneal Cancer 1 2 Completed Treatment Non-cutaneous Squamous Cell Carcinoma of Head and Neck 1 2 Recruiting Treatment Cutaneous Melanoma / Mucosal Melanoma 1 1, 2 Completed Treatment Advanced Solid Tumors 2 1, 2 Recruiting Treatment Advanced Solid Tumors 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at September 13, 2023 18:50 / Updated at September 15, 2023 10:38