FAPi-46 GA-68

Identification

Generic Name
FAPi-46 GA-68
DrugBank Accession Number
DB18827
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 950.876
Monoisotopic: 950.335387186
Chemical Formula
C41H54F2GaN11O9
Synonyms
  • [68Ga]Ga-FAPI-46
  • Gallium Ga 68 FAPi-46
  • Gallium-68-FAPi-46
External IDs
  • FAPI-46 GA-68

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
7X34CP0VEL
CAS number
2374784-98-0
InChI Key
YRZMUMGVTRNFAJ-DJJSLDLFSA-K
InChI
InChI=1S/C41H57F2N11O9.Ga/c1-47(30-3-4-34-33(21-30)32(5-6-45-34)40(63)46-24-35(55)54-29-41(42,43)22-31(54)23-44)7-2-8-48-17-19-53(20-18-48)36(56)25-49-9-11-50(26-37(57)58)13-15-52(28-39(61)62)16-14-51(12-10-49)27-38(59)60;/h3-6,21,31H,2,7-20,22,24-29H2,1H3,(H,46,63)(H,57,58)(H,59,60)(H,61,62);/q;+3/p-3/t31-;/m0./s1/i;1-2
IUPAC Name
SMILES
[68Ga+3].[H][C@]1(CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C12)N(C)CCCN1CCN(CC1)C(=O)CN1CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)C#N

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
2RecruitingDiagnosticFAP / Pancreatic Ductal Adenocarcinoma (PDAC)1somestatusstop reasonjust information to hide
2RecruitingDiagnosticLocalized Pancreatic Adenocarcinoma / Resectable Pancreatic Ductal Adenocarcinoma (PDAC) / Stage 0 Pancreatic Cancer AJCC v8 / Stage I Pancreatic Cancer AJCC v8 / Stage IIA Pancreatic Cancer AJCC v81somestatusstop reasonjust information to hide
1RecruitingBasic ScienceBladder Carcinoma / Cancer of Unknown Primary Site / Cervical Carcinoma / Cholangiocarcinoma / Hematopoietic and Lymphoid System Neoplasm / Hepatocellular Carcinoma / Malignant Adrenal Gland Neoplasm / Malignant Brain Neoplasm / Malignant Pleural Neoplasm / Malignant Solid Neoplasms / Malignant Thymus Neoplasm / Neuroendocrine Tumors / Skin Neoplasm Malignant / Testicular neoplasms malignant / Thyroid Gland Carcinoma / Urothelial Carcinoma1somestatusstop reasonjust information to hide
0RecruitingDiagnosticAlveolitis, Extrinsic Allergic / Drug-Induced Pneumonitis / Idiopathic Interstitial Pneumonias / Interstitial Lung Disease / Pneumoconiosis / Pulmonary Fibrosis / Radiation Pneumonitis1somestatusstop reasonjust information to hide
0RecruitingDiagnosticMetastatic Sarcoma / Recurrent Sarcoma / Sarcomas1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 24, 2024 23:14 / Updated at June 28, 2024 04:48