MK-8777

DB18904InvestigationalSmall molecule

MK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder...

Formula / weight: C₁₁H₁₂N₂O₂ · 204.229 g/mol (avg)
Also known as: 5H,7H-PYRIDO(3,2-F)PYRROLO(2,1-C)(1,4)OXAZEPIN-5-ONE, 8,9,9A,10-TETRAHYDRO-, (9AS)-
Code names: MK-8777 · ORG-26576

Resolves to

Compound

UNII0H1IDR8Z4FCAS1026791-61-6ChEMBLCHEMBL4303417

Structure

InChIKeyFIKUEZUFASUKAH-QMMMGPOBSA-NSMILES[H][C@@]12CCCN1C(=O)C1=CC=CN=C1OC2

What you can answer from here — as of April 23, 2025

2Clinical trialsPhase, status and sponsor resolved per trial

Which companies are running trials of MK-8777, in which indications and phases, and which of those programs are still active?

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