Arterolane

DB19027InvestigationalSmall molecule

Arterolane is under investigation in clinical trial NCT03452475 (Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+mefloquine Versus Artemether-lumefantrine in Kenyan Children).

Chemical structure of Arterolane
Mechanism
Curator reviewed
Formula / weight
C22H36N2O4 · 392.54 g/mol (avg)
Also known as
Dispiro(cyclohexane-1,3'-(1,2,4)trioxolane-5',2''-tricyclo(3.3.1.13,7)decane)-4-acetamide, n-(2-amino-2-methylpropyl)-, cis-
Code names
OZ-277 · RBX-11160

Resolves to

Compound
UNII3N1TN351VBCAS664338-39-0ChEMBLCHEMBL1197433
Clinical / RWD
ATCP01BX02
Structure
InChIKeyVXYZBLXGCYNIHP-ACBWXVLLSA-NSMILESCC(C)(N)CNC(=O)C[C@H]1CC[C@@]2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3
Targets
A0A7D3UWD9kelch13

What you can answer from here — as of September 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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1ATC codeIncluding every combination product, plus 10 drug categories
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2+ReferencesStructured and connected to the statements they support
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