Bemnifosbuvir

DB19050InvestigationalSmall molecule

Bemnifosbuvir is under investigation in clinical trial NCT05629962 (SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-risk Outpatients With COVID-19).

Formula / weight: C₂₄H₃₃FN₇O₇P · 581.542 g/mol (avg)
Also known as: (s)-isopropyl 2-((s)-(((2r,3r,4r,5r)-5-(2-amino-6-(methylamino)-9h-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate · At-527 free base · L-alanine, n-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-, 1-methylethyl ester
Code names: AT-527

Resolves to

Compound

UNII7UM3SQL968CAS1998705-64-8

Structure

InChIKeyOISLSHLAXHALQZ-LZEIJKKFSA-NSMILESCNC1=C2N=CN([C@@H]3O[C@H](CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC4=CC=CC=C4)[C@@H](O)[C@@]3(C)F)C2=NC(N)=N1

Targets

P26662Genome polyprotein

What you can answer from here — as of September 26, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

16Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bemnifosbuvir, and which of those have an active Phase 3 trial?

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