Bemnifosbuvir
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Bemnifosbuvir
- DrugBank Accession Number
- DB19050
- Background
Bemnifosbuvir is under investigation in clinical trial NCT05629962 (SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-risk Outpatients With COVID-19).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 581.542
Monoisotopic: 581.216311592 - Chemical Formula
- C24H33FN7O7P
- Synonyms
- (s)-isopropyl 2-((s)-(((2r,3r,4r,5r)-5-(2-amino-6-(methylamino)-9h-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
- At-527 free base
- L-alanine, n-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-, 1-methylethyl ester
- N-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-l-alanine 1-methylethyl ester
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 7UM3SQL968
- CAS number
- 1998705-64-8
- InChI Key
- OISLSHLAXHALQZ-LZEIJKKFSA-N
- InChI
- InChI=1S/C24H33FN7O7P/c1-13(2)37-21(34)14(3)31-40(35,39-15-9-7-6-8-10-15)36-11-16-18(33)24(4,25)22(38-16)32-12-28-17-19(27-5)29-23(26)30-20(17)32/h6-10,12-14,16,18,22,33H,11H2,1-5H3,(H,31,35)(H3,26,27,29,30)/t14-,16+,18+,22+,24+,40+/m0/s1
- IUPAC Name
- SMILES
- CNC1=C2N=CN([C@@H]3O[C@H](CO[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC4=CC=CC=C4)[C@@H](O)[C@@]3(C)F)C2=NC(N)=N1
References
- General References
- Not Available
- External Links
- ChemSpider
- 112747221
- BindingDB
- 476337
- Wikipedia
- Bemnifosbuvir
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data3 Active Not Recruiting Treatment Coronavirus Disease 2019 (COVID‑19) 1 somestatus stop reason just information to hide 2 Recruiting Treatment Chronic Hepatitis C Virus (HCV) Infection / Cirrhosis of the Liver / Hepatitis C Virus (HCV) Infection 1 somestatus stop reason just information to hide 1 Completed Treatment Healthy Volunteers Study 3 somestatus stop reason just information to hide 1 Not Yet Recruiting Treatment Healthy Volunteers Study 1 somestatus stop reason just information to hide 1 Recruiting Treatment Healthy Volunteers (HV) / Hepatic Impairment 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 03, 2024 13:14 / Updated at July 04, 2024 03:36