Deupirfenidone

DB19056InvestigationalSmall molecule

Deupirfenidone is under investigation in clinical trial NCT05321420 (LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

Chemical structure of Deupirfenidone
Formula / weight
C12H11NO · 188.244 g/mol (avg)
Also known as
1-phenyl-5-(trideuteriomethyl)-1,2-dihydropyridin-2-one · 2(1h)-pyridinone, 5-(methyl-d3)-1-phenyl-
Code names
LYT-100 · SD-560

Resolves to

Compound
UNII1QC36BHI6SCAS1093951-85-9
Structure
InChIKeyISWRGOKTTBVCFA-FIBGUPNXSA-NSMILES[2H]C([2H])([2H])C1=CN(C(=O)C=C1)C1=CC=CC=C1

What you can answer from here — as of July 20, 2026

5Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Deupirfenidone, in which indications and phases, and which of those programs are still active?

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