IMT-288
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- IMT-288
- DrugBank Accession Number
- DB19068
- Background
IMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 1452.593
Monoisotopic: 1451.715726599 - Chemical Formula
- C64H97N19O20
- Synonyms
- (4R)-5-(((1R)-1-CARBAMOYL-5-((2-((4-(2-(1H-IMIDAZOL-5-YL)ETHYLAMINO)-4-OXO-BUTANOYL)AMINO)ACETYL)AMINO)PENTYL)AMINO)-4-(((2R)-2-(((2R)-3-(4-HYDROXYPHENYL)-2-((2-(4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAZACYCLODODEC-1-YL)ACETYL)AMINO)PROPANOYL)AMINO)-6-(
- D-LYSINAMIDE, N-((4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODEC-1-YL)ACETYL)-D-TYROSYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCYL)-D-LYSYL-D-.ALPHA.-GLUTAMYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCY
- External IDs
- IMP-288
- IMT 288
- IMT-288
- IMT288
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- ECC868Y9YT
- CAS number
- 637771-94-9
- InChI Key
- AUULGUVUMUKNPY-OGBYROOVSA-N
- InChI
- InChI=1S/C64H97N19O20/c65-61(100)46(5-1-3-19-68-54(89)34-72-52(87)14-12-50(85)70-21-17-43-32-66-40-74-43)77-63(102)48(11-16-57(92)93)79-62(101)47(6-2-4-20-69-55(90)35-73-53(88)15-13-51(86)71-22-18-44-33-67-41-75-44)78-64(103)49(31-42-7-9-45(84)10-8-42)76-56(91)36-80-23-25-81(37-58(94)95)27-29-83(39-60(98)99)30-28-82(26-24-80)38-59(96)97/h7-10,32-33,40-41,46-49,84H,1-6,11-31,34-39H2,(H2,65,100)(H,66,74)(H,67,75)(H,68,89)(H,69,90)(H,70,85)(H,71,86)(H,72,87)(H,73,88)(H,76,91)(H,77,102)(H,78,103)(H,79,101)(H,92,93)(H,94,95)(H,96,97)(H,98,99)/t46-,47-,48-,49-/m1/s1
- IUPAC Name
- SMILES
- NC(=O)[C@@H](CCCCNC(=O)CNC(=O)CCC(=O)NCCC1=CN=CN1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCCCNC(=O)CNC(=O)CCC(=O)NCCC1=CN=CN1)NC(=O)[C@@H](CC1=CC=C(O)C=C1)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Completed Diagnostic Metastatic Colorectal Cancer (CRC) 1 somestatus stop reason just information to hide 1 Completed Treatment Colorectal Neoplasms 1 somestatus stop reason just information to hide 1 Withdrawn Treatment Metastatic Colorectal Cancer (CRC) 1 somestatus stop reason just information to hide 1, 2 Completed Diagnostic HER2 Negative Breast Carcinoma Expressing CEA 1 somestatus stop reason just information to hide 1, 2 Completed Diagnostic Thyroid Gland Medullary Carcinoma 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 03, 2024 14:26 / Updated at July 04, 2024 03:36