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NYX-2925

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
NYX-2925
DrugBank Accession Number
DB19149
Background

NYX-2925 is under investigation in clinical trial NCT04146896 (Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 297.355
Monoisotopic: 297.168856233
Chemical Formula
C14H23N3O4
Synonyms
  • (αS,4R)-α-[(1R)-1-Hydroxyethyl]-5-(2-methyl-1-oxopropyl)-1-oxo-2,5-diazaspiro[3.4]octane-2-acetamide
  • X062KF5ZV3
External IDs
  • CS-0113907
  • HY-135741
  • NYX-2925
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available
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Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
X062KF5ZV3
CAS number
2012536-16-0
InChI Key
NFXPEHLDVKVVKA-ISTVAULSSA-N
InChI
InChI=1S/C14H23N3O4/c1-8(2)12(20)17-6-4-5-14(17)7-16(13(14)21)10(9(3)18)11(15)19/h8-10,18H,4-7H2,1-3H3,(H2,15,19)/t9-,10+,14+/m1/s1
IUPAC Name
SMILES
C[C@@H](O)[C@H](N1C[C@]2(CCCN2C(=O)C(C)C)C1=O)C(N)=O

References

General References
Not Available
ChemSpider
128922021
ChEMBL
CHEMBL5095189

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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2CompletedSupportive CareDiabetic Peripheral Neuropathy (DPN)1somestatusstop reasonjust information to hide
2CompletedTreatmentDiabetic Peripheral Neuropathic Pain (DPN)1somestatusstop reasonjust information to hide
2CompletedTreatmentFibromyalgia2somestatusstop reasonjust information to hide
1CompletedTreatmentHealthy Volunteers (HV)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 05, 2024 14:36 / Updated at July 06, 2024 06:45