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Arketamine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Identification

Generic Name
Arketamine
DrugBank Accession Number
DB19150
Background

Arketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 237.73
Monoisotopic: 237.0920418
Chemical Formula
C13H16ClNO
Synonyms
  • (+)-ketamine
  • (r)-(+)-ketamine
  • (r)-ketamine
  • Arketamine
  • Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (2r)-
  • Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+)-
  • D-ketamine
  • Ketamine, r-
External IDs
  • HR-071603
  • J238.629A
  • PCN-101
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Y2RI13H7VW
CAS number
33643-49-1
InChI Key
YQEZLKZALYSWHR-CYBMUJFWSA-N
InChI
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1
IUPAC Name
SMILES
CN[C@]1(CCCCC1=O)C1=CC=CC=C1Cl

References

General References
Not Available
ChemSpider
559099
ChEBI
580604
ChEMBL
CHEMBL467505
ZINC
ZINC000036294079
PDBe Ligand
RKE
Wikipedia
Arketamine
PDB Entries
4f8h

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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4CompletedPreventionPostoperative pain1somestatusstop reasonjust information to hide
4CompletedTreatmentNeuropathic Pain1somestatusstop reasonjust information to hide
4Enrolling by InvitationTreatmentAcute Pain / Analgesia / Children / Delirium / Depression, Anxiety / Esketamine / Hyperalgesia / Postoperative pain / S-ketamine1somestatusstop reasonjust information to hide
4Unknown StatusTreatmentAdults / Anesthesia therapy / Postoperative pain1somestatusstop reasonjust information to hide
4Unknown StatusTreatmentAnalgesia1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 05, 2024 14:54 / Updated at July 06, 2024 06:45