Pudexacianinium

DB19161InvestigationalSmall molecule

Pudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).

Chemical structure of Pudexacianinium
Formula / weight
C135H197N4O73 · 3044.015 g/mol (avg)
Also known as
.beta.-cyclodextrin, 2a-o-(3-aminopropyl)-, diamide with 3-(2-carboxyethyl)-2-(2-(3-(2-(3-(2-carboxyethyl)-1,3-dihydro-1,1-dimethyl-2h-benz(e)indol-2-ylidiene)ethylidene)-2-methoxy-1-cyclohexen-1-yl)ethylene)-1,1-dimethyl-1h-benz(e)indolium ion · 3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-2-((1E)-2-((3E)-3-((2E)-2-(3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-1,1-DIMETHYL-1,3-DIHYDRO-2H-BENZO(E)INDOL-2-YLIDENE)ETHYLIDENE)-2-METHOXYCYCLOHEX-1-EN-1-YL)ETHEN-1-Y · Pudexacianinium ion
Code names
ASP-5354

Resolves to

Structure
InChIKeyYTSRTYDSGUUGAS-ZKNIEEHQSA-OSMILES[H][C@@]12O[C@H](CO)[C@@]([H])(O[C@@]3([H])O[C@H](CO)[C@@]([H])(O[C@@]4([H])O[C@H](CO)[C@@]([H])(O[C@@]5([H])O[C@H](CO)[C@@]([H])(O[C@@]6([H])O[C@H](CO)[C@@]([H])(O[C@@]7([H])O[C@H](CO)[C@@]([H])(O[C@@]8([H])O[C@H](CO)[C@@]([H])(O1)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](OCCCNC(=O)CC[N+]1=C(\C=C\C6=C(OC)C(CCC6)=C\C=C6\N(CCC(=O)NCCCO[C@@H]7[C@@H](O)[C@]8([H])O[C@@]9([H])O[C@H](CO)[C@@]([H])(O[C@@]%10([H])O[C@H](CO)[C@@]([H])(O[C@@]%11([H])O[C@H](CO)[C@@]([H])(O[C@@]%12([H])O[C@H](CO)[C@@]([H])(O[C@@]%13([H])O[C@H](CO)[C@@]([H])(O[C@@]%14([H])O[C@H](CO)[C@@]([H])(O[C@@]7([H])O[C@@H]8CO)[C@H](O)[C@H]%14O)[C@H](O)[C@H]%13O)[C@H](O)[C@H]%12O)[C@H](O)[C@H]%11O)[C@H](O)[C@H]%10O)[C@H](O)[C@H]9O)C7=C(C8=CC=CC=C8C=C7)C6(C)C)C(C)(C)C6=C1C=CC1=CC=CC=C61)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O

What you can answer from here — as of April 23, 2025

6Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Pudexacianinium, in which indications and phases, and which of those programs are still active?

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