Linopristin

DB19296ExperimentalSmall molecule

Linopristin is an antibiotic of the streptogramin B class. It is one part of the combination product NXL 103, along with Virginiamycin M1. The combination product was under investigation in... The combination product was under investigation in clinical trials NCT00653172 and NCT00949130 for treatment of various bacterial infections.

Chemical structure of Linopristin
Formula / weight
C50H63N9O10 · 950.107 g/mol (avg)
Also known as
Nxl-103 component rpr-202868
Code names
RPR-202868

Resolves to

Structure
InChIKeyNVGNYGXBILPHOS-VXNAYKIUSA-NSMILES[H][C@@]12CCCN1C(=O)[C@@H](CC)NC(=O)[C@@H](NC(=O)C1=NC=CC=C1O)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@]1([H])CC=C(CN3CCOCC3)CN1C(=O)[C@H](CC1=CC=C(C=C1)N(C)C)N(C)C2=O)C1=CC=CC=C1

What you can answer from here — as of March 06, 2025

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Which companies are running trials of Linopristin, in which indications and phases, and which of those programs are still active?

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