Tomligisiran

DB19330InvestigationalNucleic Acid Based Therapies

Tomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)).

Also known as
RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN-9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMI

Resolves to

What you can answer from here — as of April 23, 2025

1Clinical trialPhase, status and sponsor resolved per trial
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Which companies are running trials of Tomligisiran, in which indications and phases, and which of those programs are still active?

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