Calcimycin

DB19408InvestigationalSmall molecule

Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis. It binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in... Primarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi.

Formula / weight: C₂₉H₃₇N₃O₆ · 523.63 g/mol (avg)
Also known as: 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)- · 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-4-benzoxazolecarboxylic acid · Antibiotic a-23187
Code names: A-23187

Resolves to

Compound

UNII37H9VM9WZLCAS52665-69-7ChEMBLCHEMBL1256686ChEBI107643PubChem11957499

Structure

InChIKeyHIYAVKIYRIFSCZ-CYEMHPAKSA-NSMILES[H][C@@]1(O[C@@]2(CC[C@@H](C)[C@@H](CC3=NC4=C(C(O)=O)C(NC)=CC=C4O3)O2)[C@H](C)C[C@H]1C)[C@H](C)C(=O)C1=CC=CN1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which companies are running trials of Calcimycin, in which indications and phases, and which of those programs are still active?

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