Sematilide

DB19538ExperimentalSmall molecule

Sematilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Sematilide is a sematilide derivative class III antiarrhythmic. Sematilide has a monoisotopic...

Mechanism: Pharmacologically active on Voltage-gated inwardly rectifying potassium channel KCNH2
Curator reviewed
Formula / weight: C₁₄H₂₃N₃O₃S · 313.42 g/mol (avg)

Resolves to

Compound

UNII0NHB13IN3RCAS101526-83-4ChEMBLCHEMBL95804

Structure

InChIKeyKHYPYQZQJSBPIX-UHFFFAOYSA-NSMILESCCN(CC)CCNC(=O)C1=CC=C(NS(C)(=O)=O)C=C1

Targets

Q12809KCNH2

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sematilide, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account