Aprikalim

DB19802ExperimentalSmall molecule

Aprikalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Aprikalim is a potassium channel activator, antihypertensive. Aprikalim has a monoisotopic molecular...

Mechanism: Pharmacologically active on ATP-sensitive potassium channel
Curator reviewed
Formula / weight: C₁₂H₁₆N₂OS₂ · 268.39 g/mol (avg)

Resolves to

Compound

UNII374BH4KVRGCAS132562-26-6ChEMBLCHEMBL275459

Structure

InChIKeyGKEMHVLBZNVZOI-SJKOYZFVSA-NSMILESCNC(=S)[C@@]1(CCCC[S@+]1[O-])C1=CC=CN=C1

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which companies are running trials of Aprikalim, in which indications and phases, and which of those programs are still active?

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