Arofylline

DB20307ExperimentalSmall molecule

Arofylline is a small molecule drug. The usage of the INN stem '-fylline' in the name indicates that Arofylline is a N-methylated xanthine derivative. Arofylline has a monoisotopic molecular weight...

Mechanism: Pharmacologically active on Phosphodiesterase 4
Curator reviewed
Formula / weight: C₁₄H₁₃ClN₄O₂ · 304.73 g/mol (avg)
Code names: LAS-31025

Resolves to

Compound

UNII87L38AY71RCAS136145-07-8ChEMBLCHEMBL1598450

Structure

InChIKeyGVTLDPJNRVMCAL-UHFFFAOYSA-NSMILESCCCN1C(=O)N(C2=C(NC=N2)C1=O)C1=CC=C(Cl)C=C1

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which companies are running trials of Arofylline, in which indications and phases, and which of those programs are still active?

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