Crobenetine

DB21095InvestigationalSmall molecule

Crobenetine is a small molecule drug. Crobenetine is under investigation in clinical trial NCT02273466 (Pharmacokinetics of Oral Desipramine With and Without Concomitant Administration of Crobenetine Infusion in Healthy Male Subjects).... Crobenetine has a monoisotopic molecular weight of 379.25 Da.

Mechanism: Pharmacologically active on Voltage-gated sodium channel alpha subunit
Curator reviewed
Formula / weight: C₂₅H₃₃NO₂ · 379.544 g/mol (avg)

Resolves to

Compound

UNIIQ72DWI2G4CCAS221019-25-6ChEMBLCHEMBL3039733ChEBI755097PubChem9886143

Structure

InChIKeyVCCBCXVFGHTDQN-UODBTFMRSA-NSMILES[H][C@]12CC3=C(C=CC=C3O)[C@](C)(CCN1C[C@H](C)OCC1=CC=CC=C1)C2(C)C

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which companies are running trials of Crobenetine, in which indications and phases, and which of those programs are still active?

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