Evifacotrep

DB21510InvestigationalSmall molecule

Evifacotrep is a small molecule drug. The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist. Evifacotrep... Evifacotrep has a monoisotopic molecular weight of 441.06 Da.

Chemical structure of Evifacotrep
Formula / weight
C18H12ClF4N5O2 · 441.77 g/mol (avg)

Resolves to

Structure
InChIKeyIQFZADSTVFSHDX-UHFFFAOYSA-NSMILESFC1=CC(=C(OC2=C3CCN(CC3=NC=N2)C2=C(Cl)C(=O)NN=C2)C=C1)C(F)(F)F

What you can answer from here — as of August 31, 2026

1Clinical trialPhase, status and sponsor resolved per trial
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Which companies are running trials of Evifacotrep, in which indications and phases, and which of those programs are still active?

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