Uplarafenib

DB21661ExperimentalSmall molecule

Uplarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Uplarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. Uplarafenib has a... Uplarafenib has a monoisotopic molecular weight of 494.12 Da.

Chemical structure of Uplarafenib
Formula / weight
C22H21F3N4O4S ยท 494.49 g/mol (avg)

Resolves to

Compound
UNIITQU3V7CXC3CAS1425485-87-5ChEMBLCHEMBL5314547
Structure
InChIKeyHAYBWDINAFTFCJ-UHFFFAOYSA-NSMILESCCCS(=O)(=O)NC1=CC(F)=C(F)C(C(=O)C2=CC3=NC(=CN=C3C=C2)N2CCOCC2)=C1F

Which companies are running trials of Uplarafenib, in which indications and phases, and which of those programs are still active?

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