Flezurafenib

DB21725ExperimentalSmall molecule

Flezurafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Flezurafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. Flezurafenib has a... Flezurafenib has a monoisotopic molecular weight of 456.16 Da.

Chemical structure of Flezurafenib
Formula / weight
C26H21FN4O3 ยท 456.477 g/mol (avg)

Resolves to

Structure
InChIKeyTWJSMWXWCWQPRO-QGZVFWFLSA-NSMILESFC1=CC=C(C=C1)C1=CNC(=N1)[C@H]1COC2=CC=C(OC3=CC=NC4=C3CCC(=O)N4)C=C2C1

Which companies are running trials of Flezurafenib, in which indications and phases, and which of those programs are still active?

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