Vormatrigine

DB21731InvestigationalSmall molecule

Vormatrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Vormatrigine is a sodium channel blocker, signal transduction modulator. Vormatrigine has a... Vormatrigine has a monoisotopic molecular weight of 406.09 Da.

Mechanism: Pharmacologically active on Sodium channel protein
Curator reviewed
Formula / weight: C₁₆H₁₂F₆N₄O₂ · 406.288 g/mol (avg)

Resolves to

Compound

UNIIQU3C48T4NVCAS2392951-18-5

Structure

InChIKeyVOANOFDZGYTEPX-UHFFFAOYSA-NSMILESCCOC(F)(F)C1=NN=C2C=CC(=CN12)C1=CC(F)=C(OCC(F)(F)F)N=C1

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which companies are running trials of Vormatrigine, in which indications and phases, and which of those programs are still active?

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