CX-051869

DB31656ApprovedVaccines

CX-051869 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage LP.8.1. It is the active ingredient of the 2025-2026 formulation of...

Primary indication
CX-051869, as the active ingredient in the 2024-2025 formulation of Spikevax, is indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients ≥65 years...Curator reviewed
First approval
United States, 2025
Also known as
Spikevax (2025-2026 Formula)
Code names
CX-051869

Resolves to

Clinical / RWD

What you can answer from here — as of November 20, 2025

2Marketed productsAcross 1 country and 1 labeller
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1+ReferenceStructured and connected to the statements they support
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Which companies are running trials of CX-051869, in which indications and phases, and which of those programs are still active?

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