FRAX1036

DB31834ExperimentalSmall molecule

FRAX1036 is a p21-activated kinase (PAK) inhibitor.

Mechanism: Pharmacologically active on Serine/threonine-protein kinase PAK 1 and Serine/threonine-protein kinase PAK 4
Curator reviewed
Formula / weight: C₂₈H₃₂ClN₇O · 518.06 g/mol (avg)
Code names: FRAX-1036

Resolves to

Compound

Structure

InChIKeyRYCBSFIKWACFBY-UHFFFAOYSA-NSMILESCCN1C(=O)C(=CC2=CN=C(NCCC3CCN(C)CC3)N=C12)C1=C(Cl)C=C(C=C1)C1=NC(C)=CN=C1

Targets

What you can answer from here — as of August 31, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with FRAX1036, and which of those have an active Phase 3 trial?

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