SW033291

DB32765ExperimentalSmall molecule

SW033291 is a small molecule 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. It has been found to increase prostaglandin E2 (PGE2) and is being investigated in accelerating of hematopoietic recovery and treating type...

Mechanism: Pharmacologically active on 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
Curator reviewed
Formula / weight: C₂₁H₂₀N₂OS₃ · 412.58 g/mol (avg)
Also known as: 2-(Butane-1-sulfinyl)-4-phenyl-6-thiophen-2-yl-thieno[2,3-b]pyridin-3-ylamine
Code names: SW033291

Resolves to

Compound

CAS459147-39-8ChEMBLCHEMBL4061483

Structure

InChIKeyLCYAYKSMOVLVRL-UHFFFAOYSA-NSMILESCCCCS(=O)C1=C(N)C2=C(C=C(N=C2S1)C1=CC=CS1)C1=CC=CC=C1

Targets

P15428HPGD

What you can answer from here — as of August 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

16+ReferencesStructured and connected to the statements they support

Which drugs share a target with SW033291, and which of those have an active Phase 3 trial?

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