Terbinafine hydrochlorideProduct ingredient for Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.^10,11 It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.¹ Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.^1,2,11

Terbinafine hydrochloride was granted FDA approval on 30 December 1992.⁹