Methylprednisolone acetateProduct ingredient for Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone.⁹ It was first described in the literature in the late 1950s.^9,10

Methylprednisolone was granted FDA approval on 24 October 1957.¹² In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.¹¹ The efficacy of methylprednisolone in novel coronavirus pneumonia is being investigated further in clinical trials.¹⁵