Methenamine hippurateProduct ingredient for Methenamine
- Name
- Methenamine hippurate
- Drug Entry
- Methenamine
Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
- Accession Number
- DBSALT001270
- Structure
Structure for Methenamine hippurate (DBSALT001270)
- Synonyms
- Hexamethylenetetramine monohippurate / Hexamine hippurate / Hiprex
- UNII
- M329791L57
- CAS Number
- 5714-73-8
- Weight
- Average: 319.365
Monoisotopic: 319.164439556 - Chemical Formula
- C15H21N5O3
- InChI Key
- ROAIXOJGRFKICW-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H9NO3.C6H12N4/c11-8(12)6-10-9(13)7-4-2-1-3-5-7;1-7-2-9-4-8(1)5-10(3-7)6-9/h1-5H,6H2,(H,10,13)(H,11,12);1-6H2
- IUPAC Name
- 1,3,5,7-tetraazatricyclo[3.3.1.1³,⁷]decane; 2-(phenylformamido)acetic acid
- SMILES
- C1N2CN3CN1CN(C2)C3.OC(=O)CNC(=O)C1=CC=CC=C1
- External Links
- KEGG Drug
- D00855
- ChemSpider
- 20623
- ChEBI
- 6825
- ChEMBL
- CHEMBL1201104
- Wikipedia
- Hexamethylenetetramine
- Predicted Properties
Property Value Source Water Solubility 1.18 mg/mL ALOGPS logP 0.23 ALOGPS logP 0.53 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) 3.59 Chemaxon pKa (Strongest Basic) -1.3 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 66.4 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 46.12 m3·mol-1 Chemaxon Polarizability 17.6 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon