Pimagedine hydrochlorideProduct ingredient for Pimagedine
- Name
- Pimagedine hydrochloride
- Drug Entry
- Pimagedine
Pimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease. It is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies. It is beneficial in treating patients with diabetic nephropathy.
- Accession Number
- DBSALT002490
- Structure
- Synonyms
- Aminoguanidine HCl / Aminoguanidine hydrochloride / Aminoguanidine monohydrochloride / Pimagedine HCl / Pimagedine hydrochloride
- External IDs
- GER-11
- UNII
- A2Z7G2RGAH
- CAS Number
- 1937-19-5
- Weight
- Average: 110.546
Monoisotopic: 110.035923951 - Chemical Formula
- CH7ClN4
- InChI Key
- UBDZFAGVPPMTIT-UHFFFAOYSA-N
- InChI
- InChI=1S/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H
- IUPAC Name
- N-azaniumylguanidine chloride
- SMILES
- [Cl-].NC(=N)N[NH3+]
- External Links
- ChemSpider
- 15211
- ChEMBL
- CHEMBL1256292
- Predicted Properties
Property Value Source Water Solubility 11.1 mg/mL ALOGPS logP -2.7 ALOGPS logP -1.5 Chemaxon logS -1 ALOGPS pKa (Strongest Basic) 12.01 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 89.54 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 51.07 m3·mol-1 Chemaxon Polarizability 7.29 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon