Primary Myelofibrosis (PMF)

Also known as: Primary Myelofibrosis / Primary Myelofibrosis (MF) / Myelofibrosis (PMF) / Myelofibrosis, Primary / PMF / Osteomyelofibrosis / Primary myelofibrosis (disorder) / Myelofibrosis (disorder) / Primary myelofibrosis (morphologic abnormality)

DrugDrug NameDrug Description
DB12500FedratinibFedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis.[L8090,L47016]
DB08877RuxolitinibA kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Completed1
DB00099Filgrastim0Completed1
DB01073Fludarabine0Completed1
DB00888Mechlorethamine0Completed1
DB00688Mycophenolate mofetil0Completed1
DB09036Siltuximab0Withdrawn1
DB00864Tacrolimus0Completed1
DB18454AVID-2001Completed1
DB12588AZD-14801Completed1
DB12001Abemaciclib1Terminated1
DB05812Abiraterone1Terminated1
DB08916Afatinib1Terminated1
DB00062Albumin human1Terminated1
DB01169Arsenic trioxide1Terminated1
DB09495Avobenzone1Terminated1
DB00928Azacitidine1Completed2
DB05015Belinostat1Completed1
DB00112Bevacizumab1Terminated1
DB01128Bicalutamide1Terminated1
DB00188Bortezomib1Terminated1
DB16741Bortezomib D-mannitol1Terminated1
DB01008Busulfan1Completed1
DB06772Cabazitaxel1Terminated1
DB08875Cabozantinib1Terminated1
DB01101Capecitabine1Terminated1
DB00958Carboplatin1Terminated1
DB01413Cefepime1Completed1
DB00482Celecoxib1Terminated1
DB05239Cobimetinib1Terminated1
DB12483Copanlisib1Terminated1
DB00531Cyclophosphamide1Completed1
DB00987Cytarabine1Completed1
DB08912Dabrafenib1Terminated1
DB11963Dacomitinib1Terminated1
DB12941Darolutamide1Terminated1
DB01254Dasatinib1Terminated1
DB00694Daunorubicin1Terminated1
DB01262Decitabine1Completed1
DB01262Decitabine1Withdrawn1
DB00997Doxorubicin1Terminated1
DB11714Durvalumab1Terminated1
DB11714Durvalumab1Withdrawn1
DB13874Enasidenib1Terminated1
DB11986Entrectinib1Terminated1
DB08899Enzalutamide1Terminated1
DB00530Erlotinib1Terminated1
DB00773Etoposide1Completed1
DB01590Everolimus1Terminated1
DB00099Filgrastim1Completed1
DB01073Fludarabine1Completed2
DB01073Fludarabine1Withdrawn1
DB00544Fluorouracil1Terminated1
DB12396Fresolimumab1Terminated1
DB13040Gandotinib1Completed1
DB09054Idelalisib1Terminated1
DB00619Imatinib1Completed1
DB00619Imatinib1Terminated1
DB06186Ipilimumab1Terminated1
DB09078Lenvatinib1Terminated1
DB00650Leucovorin1Terminated1
DB12130Lorlatinib1Terminated1
DB00678Losartan1Terminated1
DB00888Mechlorethamine1Completed1
DB00888Mechlorethamine1Withdrawn1
DB00688Mycophenolate mofetil1Completed1
DB00688Mycophenolate mofetil1Terminated1
DB11828Neratinib1Terminated1
DB17561Nisevokitug1Withdrawn1
DB09035Nivolumab1Terminated1
DB09496Octinoxate1Terminated1
DB09074Olaparib1Terminated1
DB00526Oxaliplatin1Terminated1
DB01229Paclitaxel1Terminated1
DB11697Pacritinib1Recruiting1
DB09073Palbociclib1Terminated1
DB06603Panobinostat1Terminated1
DB09037Pembrolizumab1Terminated1
DB06366Pertuzumab1Terminated1
DB08901Ponatinib1Terminated1
DB08896Regorafenib1Terminated1
DB08877Ruxolitinib1Completed1
DB08877Ruxolitinib1Terminated2
DB08877Ruxolitinib1Withdrawn1
DB16322Sabatolimab1Withdrawn1
DB00877Sirolimus1Completed2
DB00877Sirolimus1Terminated2
DB00877Sirolimus1Withdrawn1
DB09143Sonidegib1Completed1
DB00398Sorafenib1Terminated1
DB14892Spartalizumab1Withdrawn1
DB01268Sunitinib1Completed1
DB01268Sunitinib1Terminated1
DB00864Tacrolimus1Completed1
DB00864Tacrolimus1Withdrawn1
DB11760Talazoparib1Recruiting1
DB08911Trametinib1Terminated1
DB05773Trastuzumab emtansine1Terminated1
DB00755Tretinoin1Terminated1
DB08881Vemurafenib1Terminated1
DB11581Venetoclax1Terminated1
DB08828Vismodegib1Terminated1
DB02546Vorinostat1Completed1
DB02546Vorinostat1Terminated1
DB12638Zelavespib1Terminated2
DB17234Bomedemstat1 / 2Completed1
DB01008Busulfan1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB12500Fedratinib1 / 2Active Not Recruiting1
DB01073Fludarabine1 / 2Completed1
DB15126IMG-72891 / 2Completed1
DB12784Ilginatinib1 / 2Completed1
DB11763Momelotinib1 / 2Completed2
DB15299Navtemadlin1 / 2Recruiting1
DB06603Panobinostat1 / 2Unknown Status1
DB17129Pelabresib anhydrous1 / 2Active Not Recruiting1
DB08910Pomalidomide1 / 2Active Not Recruiting1
DB08877Ruxolitinib1 / 2Active Not Recruiting2
DB08877Ruxolitinib1 / 2Completed2
DB08877Ruxolitinib1 / 2Recruiting1
DB09143Sonidegib1 / 2Completed1
DB00945Acetylsalicylic acid2Completed1
DB06605Apixaban2Completed1
DB00928Azacitidine2Recruiting1
DB00394Beclomethasone dipropionate2Completed1
DB11105Benzalkonium2Active Not Recruiting1
DB17234Bomedemstat2Active Not Recruiting1
DB01008Busulfan2Active Not Recruiting1
DB01008Busulfan2Completed1
DB01008Busulfan2Recruiting1
DB01008Busulfan2Terminated1
DB06168Canakinumab2Recruiting1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Recruiting3
DB00531Cyclophosphamide2Terminated1
DB00091Cyclosporine2Completed1
DB01406Danazol2Completed1
DB01262Decitabine2Active Not Recruiting1
DB01262Decitabine2Recruiting1
DB01609Deferasirox2Completed1
DB01609Deferasirox2Terminated1
DB06317Elotuzumab2Recruiting1
DB12500Fedratinib2Recruiting3
DB00099Filgrastim2Recruiting1
DB01073Fludarabine2Active Not Recruiting2
DB01073Fludarabine2Completed5
DB01073Fludarabine2Recruiting2
DB01073Fludarabine2Terminated1
DB05036Grn163l2Completed1
DB15126IMG-72892Active Not Recruiting1
DB12784Ilginatinib2Terminated1
DB00619Imatinib2Completed1
DB14909Imetelstat2Completed1
DB05258Interferon alfa2Active Not Recruiting1
DB12154Itacitinib2Active Not Recruiting1
DB12154Itacitinib2Recruiting1
DB17545Jaktinib2Completed1
DB12085LCL-1612Completed1
DB00480Lenalidomide2Completed1
DB12281Luspatercept2Completed1
DB00888Mechlorethamine2Active Not Recruiting2
DB00888Mechlorethamine2Recruiting2
DB01042Melphalan2Completed1
DB16620Methopterin2Active Not Recruiting1
DB16620Methopterin2Recruiting1
DB00563Methotrexate2Active Not Recruiting1
DB00563Methotrexate2Completed2
DB00563Methotrexate2Recruiting1
DB08893Mirabegron2Completed1
DB11763Momelotinib2Active Not Recruiting1
DB11763Momelotinib2Completed3
DB00688Mycophenolate mofetil2Active Not Recruiting1
DB00688Mycophenolate mofetil2Completed4
DB00688Mycophenolate mofetil2Recruiting2
DB15299Navtemadlin2Recruiting1
DB09035Nivolumab2Recruiting1
DB09035Nivolumab2Terminated1
DB00904Ondansetron2Completed1
DB16735PAT-12512Withdrawn1
DB11697Pacritinib2Completed1
DB11697Pacritinib2Recruiting1
DB11697Pacritinib2Withdrawn1
DB06603Panobinostat2Terminated1
DB05922Patidegib2Completed1
DB12655Patidegib2Completed1
DB09037Pembrolizumab2Completed1
DB00635Prednisone2Completed1
DB00172Proline2Active Not Recruiting1
DB12614Reparixin2Recruiting1
DB15119Ropeginterferon alfa-2b2Active Not Recruiting1
DB08877Ruxolitinib2Active Not Recruiting1
DB06164Ruxolitinib2Completed1
DB08877Ruxolitinib2Completed5
DB08877Ruxolitinib2Not Yet Recruiting1
DB08877Ruxolitinib2Recruiting4
DB08877Ruxolitinib2Terminated2
DB11942Selinexor2Active Not Recruiting1
DB00877Sirolimus2Active Not Recruiting1
DB01268Sunitinib2Terminated1
DB00864Tacrolimus2Active Not Recruiting2
DB00864Tacrolimus2Completed4
DB00864Tacrolimus2Recruiting3
DB05861Tasquinimod2Not Yet Recruiting1
DB01041Thalidomide2Completed1
DB04960Tipifarnib2Completed1
DB11940Triapine2Completed1
DB14852Zinpentraxin alfa2Completed1
DB06210Eltrombopag2 / 3Completed1
DB15299Navtemadlin2 / 3Recruiting1
DB17234Bomedemstat3Recruiting1
DB01406Danazol3Completed1
DB01406Danazol3Recruiting1
DB12500Fedratinib3Active Not Recruiting1
DB12500Fedratinib3Completed1
DB01005Hydroxyurea3Completed1
DB01005Hydroxyurea3Recruiting1
DB15126IMG-72893Recruiting1
DB05258Interferon alfa3Completed1
DB12281Luspatercept3Recruiting1
DB11763Momelotinib3Completed3
DB11697Pacritinib3Recruiting1
DB11697Pacritinib3Terminated2
DB14867Parsaclisib3Active Not Recruiting2
DB14867Parsaclisib3Not Yet Recruiting1
DB14867Parsaclisib3Recruiting1
DB00008Peginterferon alfa-2a3Completed1
DB00022Peginterferon alfa-2b3Completed1
DB17129Pelabresib anhydrous3Active Not Recruiting1
DB08910Pomalidomide3Completed1
DB08877Ruxolitinib3Active Not Recruiting3
DB08877Ruxolitinib3Completed2
DB08877Ruxolitinib3Not Yet Recruiting1
DB08877Ruxolitinib3Recruiting2
DB06603Panobinostat4Recruiting1
DB08877Ruxolitinib4Completed1
DB08877Ruxolitinib4Recruiting1
DB05220AlisertibNot AvailableActive Not Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableCompleted1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01008BusulfanNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
DB00091CyclosporineNot AvailableCompleted1
DB12500FedratinibNot AvailableRecruiting2
DB01073FludarabineNot AvailableCompleted2
DB00529FoscarnetNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB14509Lithium carbonateNot AvailableCompleted1
DB12281LuspaterceptNot AvailableRecruiting1
DB01042MelphalanNot AvailableCompleted1
DB00563MethotrexateNot AvailableCompleted1
DB11763MomelotinibNot AvailableNo Longer Available1
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB00039PaliferminNot AvailableCompleted1
DB08877RuxolitinibNot AvailableAvailable1
DB00864TacrolimusNot AvailableCompleted1
DB01610ValganciclovirNot AvailableCompleted1