Spastic Pain of the Gastrointestinal Tract

DrugDrug NameDrug Description
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB06751DrotaverineA phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
DB13581RociverineAn antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms.
DrugDrug NameTargetType
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB06751DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB06751DrotaverineVoltage-dependent L-type calcium channeltarget
DB13581RociverineMuscarinic acetylcholine receptor M1target
DB13581RociverineMuscarinic acetylcholine receptor M2target
DB13581RociverineMuscarinic acetylcholine receptor M3target
DB13581RociverineMuscarinic acetylcholine receptor M4target
DB13581RociverineMuscarinic acetylcholine receptor M5target
DrugDrug NamePhaseStatusCount