Fusion glycoprotein F0

Details

Name
Fusion glycoprotein F0
Synonyms
Not Available
Gene Name
F
Organism
Human respiratory syncytial virus A (strain A2)
Amino acid sequence
>lcl|BSEQ0052802|Fusion glycoprotein F0
MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIE
LSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPPTNNRARRELPRFMNYTLN
NAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVS
LSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVN
AGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYV
VQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKV
QSNRVFCDTMNSLTLPSEINLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKT
KCTASNKNRGIIKTFSNGCDYVSNKGMDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDP
LVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTTNIMITTIIIVIIVILLS
LIAVGLLLYCKARSTPVTLSKDQLSGINNIAFSN
Number of residues
574
Molecular Weight
63452.745
Theoretical pI
Not Available
GO Classification
Functions
identical protein binding
Processes
entry receptor-mediated virion attachment to host cell / fusion of virus membrane with host plasma membrane / positive regulation of syncytium formation by virus / viral entry into host cell
Components
host cell Golgi membrane / host cell plasma membrane / integral component of membrane / viral envelope / virion membrane
General Function
Fusion glycoprotein F0 Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins.
Specific Function
Identical protein binding
Pfam Domain Function
Transmembrane Regions
525-550
Cellular Location
Host Golgi apparatus membrane
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP03420
UniProtKB Entry NameFUS_HRSVA
General References
Not Available

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB16258Nirsevimabapproved, investigationalyesantibodyDetails