Cytochrome c oxidase subunit 2
Details
- Name
- Cytochrome c oxidase subunit 2
- Synonyms
- 1.9.3.1
- coiI
- ctaB
- Cytochrome aa3 subunit 2
- Cytochrome c oxidase polypeptide II
- Oxidase aa(3) subunit 2
- Gene Name
- ctaC
- Organism
- Paracoccus denitrificans
- Amino acid sequence
>lcl|BSEQ0012898|Cytochrome c oxidase subunit 2 MMAIATKRRGVAAVMSLGVATMTAVPALAQDVLGDLPVIGKPVNGGMNFQPASSPLAHDQ QWLDHFVLYIITAVTIFVCLLLLICIVRFNRRANPVPARFTHNTPIEVIWTLVPVLILVA IGAFSLPILFRSQEMPNDPDLVIKAIGHQWYWSYEYPNDGVAFDALMLEKEALADAGYSE DEYLLATDNPVVVPVGKKVLVQVTATDVIHAWTIPAFAVKQDAVPGRIAQLWFSVDQEGV YFGQCSELCGINHAYMPIVVKAVSQEKYEAWLAGAKEEFAADASDYLPASPVKLASAE
- Number of residues
- 298
- Molecular Weight
- 32538.495
- Theoretical pI
- 4.7
- GO Classification
- Functionscopper ion binding / cytochrome-c oxidase activityProcesseselectron transport chainComponentsintegral component of membrane / plasma membrane / respiratory chain
- General Function
- Cytochrome-c oxidase activity
- Specific Function
- Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
- Pfam Domain Function
- Transmembrane Regions
- 56-88 104-134
- Cellular Location
- Cell inner membrane
- Gene sequence
>lcl|BSEQ0007921|897 bp ATGATGGCAATTGCGACCAAGCGCCGCGGGGTGGCGGCGGTGATGAGCCTGGGAGTTGCG ACGATGACGGCCGTGCCGGCCTTGGCGCAGGACGTGCTGGGCGATCTGCCGGTGATCGGC AAGCCGGTGAACGGCGGGATGAACTTCCAACCGGCGTCGAGCCCGCTGGCGCATGACCAG CAATGGCTGGATCATTTCGTGCTCTACATCATCACGGCCGTGACGATCTTCGTCTGCCTG CTGCTGCTGATCTGCATCGTCCGTTTCAACCGCCGGGCGAATCCGGTGCCGGCGCGCTTT ACCCACAACACCCCGATCGAGGTGATCTGGACCCTGGTCCCGGTGCTGATCCTGGTGGCG ATCGGGGCCTTCTCGCTGCCGATCCTGTTCCGCAGCCAGGAGATGCCGAACGATCCCGAC CTGGTGATCAAGGCCATCGGCCACCAGTGGTACTGGTCCTATGAATACCCCAATGACGGC GTCGCCTTCGACGCGCTGATGCTGGAGAAAGAGGCCCTGGCCGATGCCGGCTATTCCGAG GACGAGTATCTGCTGGCGACCGACAACCCGGTCGTGGTTCCGGTCGGCAAGAAGGTCCTG GTCCAGGTGACCGCGACCGACGTGATCCACGCCTGGACCATCCCCGCCTTCGCCGTCAAG CAGGACGCCGTGCCGGGCCGCATCGCGCAGCTGTGGTTCTCGGTCGACCAGGAGGGCGTC TATTTCGGCCAGTGCTCCGAGCTTTGCGGCATCAACCACGCCTATATGCCCATCGTCGTC AAGGCGGTCAGCCAGGAGAAATACGAAGCCTGGCTTGCCGGCGCGAAAGAGGAATTCGCC GCCGACGCCTCGGACTACCTGCCCGCCAGCCCCGTCAAGCTGGCCTCGGCAGAGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P08306 UniProtKB Entry Name COX2_PARDE GenBank Protein ID 45469 GenBank Gene ID X05828 - General References
- Raitio M, Jalli T, Saraste M: Isolation and analysis of the genes for cytochrome c oxidase in Paracoccus denitrificans. EMBO J. 1987 Sep;6(9):2825-33. [Article]
- Steinrucke P, Steffens GC, Panskus G, Buse G, Ludwig B: Subunit II of cytochrome c oxidase from Paracoccus denitrificans. DNA sequence, gene expression and the protein. Eur J Biochem. 1987 Sep 15;167(3):431-9. [Article]
- Iwata S, Ostermeier C, Ludwig B, Michel H: Structure at 2.8 A resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature. 1995 Aug 24;376(6542):660-9. [Article]
- Ostermeier C, Harrenga A, Ermler U, Michel H: Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10547-53. [Article]