Secretin receptor
Details
- Name
- Secretin receptor
- Synonyms
- SCT-R
- Gene Name
- SCTR
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0016064|Secretin receptor MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS NSTKASHLEQSQGTCRTSII
- Number of residues
- 440
- Molecular Weight
- 50206.135
- Theoretical pI
- 7.77
- GO Classification
- Functionssecretin receptor activityProcessescell surface receptor signaling pathway / digestion / excretion / G-protein coupled receptor signaling pathwayComponentscytoplasmic microtubule / integral component of plasma membrane / plasma membrane
- General Function
- Secretin receptor activity
- Specific Function
- This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
- Pfam Domain Function
- Transmembrane Regions
- 144-167 175-194 217-240 255-276 295-317 344-362 370-392
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0016065|Secretin receptor (SCTR) ATGCGTCCCCACCTGTCGCCGCCGCTGCAGCAGCTACTACTGCCGGTGCTGCTCGCCTGC GCCGCGCACTCGACTGGAGCCCTTCCCCGACTATGTGACGTGCTACAAGTGCTGTGGGAA GAGCAAGACCAGTGCCTGCAGGAACTCTCCAGAGAGCAGACAGGAGACCTGGGCACGGAG CAGCCAGTGCCAGGTTGTGAGGGGATGTGGGACAACATAAGCTGCTGGCCCTCTTCTGTG CCGGGCCGGATGGTGGAGGTGGAATGCCCGAGATTCCTCCGGATGCTCACCAGCAGAAAT GGTTCCTTGTTCCGAAACTGCACACAGGATGGCTGGTCAGAAACCTTCCCCAGGCCTAAT CTGGCCTGTGGCGTTAATGTGAACGACTCTTCCAACGAGAAGCGGCACTCCTACCTGCTG AAGCTGAAAGTCATGTACACCGTGGGCTACAGCTCCTCCCTGGTCATGCTCCTGGTCGCC CTTGGCATCCTCTGTGCTTTCCGGAGGCTCCACTGCACTCGCAACTACATCCACATGCAC CTGTTCGTGTCCTTCATCCTTCGTGCCCTGTCCAACTTCATCAAGGACGCCGTGCTCTTC TCCTCAGATGATGTCACCTACTGCGATGCCCACAGGGCGGGCTGCAAGCTGGTCATGGTG CTGTTCCAGTACTGCATCATGGCCAACTACTCCTGGCTGCTGGTGGAAGGCCTCTACCTT CACACACTCCTCGCCATCTCCTTCTTCTCTGAAAGAAAGTACCTCCAGGGATTTGTGGCA TTCGGATGGGGTTCTCCAGCCATTTTTGTTGCTTTGTGGGCTATTGCCAGACACTTTCTG GAAGATGTTGGGTGCTGGGACATCAATGCCAACGCATCCATCTGGTGGATCATTCGTGGT CCTGTGATCCTCTCCATCCTGATTAATTTCATCCTTTTCATAAACATTCTAAGAATCCTG ATGAGAAAACTTAGAACCCAAGAAACAAGAGGAAATGAAGTCAGCCATTATAAGCGCCTG GCCAGGTCCACTCTCCTGCTGATCCCCCTCTTTGGCATCCACTACATCGTCTTCGCCTTC TCCCCAGAGGACGCTATGGAGATCCAGCTGTTTTTTGAACTAGCCCTTGGCTCATTCCAG GGACTGGTGGTGGCCGTCCTCTACTGCTTCCTCAATGGGGAGGTGCAGCTGGAGGTTCAG AAGAAGTGGCAGCAATGGCACCTCCGTGAGTTCCCACTGCACCCCGTGGCCTCCTTCAGC AACAGCACCAAGGCCAGCCACTTGGAGCAGAGCCAGGGCACCTGCAGGACCAGCATCATC TGA
- Chromosome Location
- 2
- Locus
- 2q14.1
- External Identifiers
Resource Link UniProtKB ID P47872 UniProtKB Entry Name SCTR_HUMAN GenBank Protein ID 662796 GenBank Gene ID U20178 GenAtlas ID SCTR HGNC ID HGNC:10608 - General References
- Jiang S, Ulrich C: Molecular cloning and functional expression of a human pancreatic secretin receptor. Biochem Biophys Res Commun. 1995 Feb 27;207(3):883-90. [Article]
- Chow BK: Molecular cloning and functional characterization of a human secretin receptor. Biochem Biophys Res Commun. 1995 Jul 6;212(1):204-11. [Article]
- Patel DR, Kong Y, Sreedharan SP: Molecular cloning and expression of a human secretin receptor. Mol Pharmacol. 1995 Mar;47(3):467-73. [Article]
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