Synaptic vesicle glycoprotein 2A
Details
- Name
- Synaptic vesicle glycoprotein 2A
- Synonyms
- KIAA0736
- Gene Name
- SV2A
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0001977|Synaptic vesicle glycoprotein 2A MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEDDDDDFPA PSDGYYRGEGTQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLA GVRGGLSDGEGPPGGRGEAQRRKEREELAQQYEAILRECGHGRFQWTLYFVLGLALMADG VEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLS VNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFW MIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRF FLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRW GVRALSLGGQVWGNFLSCFGPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDY ASRTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVT SSNTFFRNCTFINTVFYNTDLFEYKFVNSRLINSTFLHNKEGCPLDVTGTGEGAYMVYFV SFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIALLCLFGG VSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFAS AALALGSSLALKLPETRGQVLQ
- Number of residues
- 742
- Molecular Weight
- 82694.665
- Theoretical pI
- 5.26
- GO Classification
- Functionsprotein kinase binding / receptor activity / transmembrane transporter activityProcessescellular calcium ion homeostasis / neurotransmitter transportComponentscell-cell junction / cytoplasm / endoplasmic reticulum / integral component of membrane / neuromuscular junction / plasma membrane / presynaptic active zone / synaptic vesicle / synaptic vesicle membrane / terminal bouton
- General Function
- Transmembrane transporter activity
- Specific Function
- Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
- Pfam Domain Function
- Transmembrane Regions
- 170-190 206-226 234-254 263-283 295-315 335-355 448-468 599-619 627-647 652-672 686-708 713-731
- Cellular Location
- Cell junction
- Gene sequence
>lcl|BSEQ0010696|Synaptic vesicle glycoprotein 2A (SV2A) ATGACTGCCTGCTTATCTTGGCCTTTGCCCACAGACCTGTTCGAGTACAAGTTTGTGAAC AGCCGTCTGATAAACAGTACATTCCTGCACAACAAGGAGGGCTGCCCGCTAGACGTGACA GGGACGGGCGAAGGTGCCTACATGGTATACTTTGTGAGCTTCCTGGGGACACTGGCAGTG CTTCCTGGGAATATCGTGTCTGCCCTGCTCATGGACAAGATCGGCAGGCTCAGAATGCTT GCTGGCTCCAGCGTGATGTCCTGTGTCTCCTGCTTCTTCCTGTCTTTTGGGAACAGTGAG TCGGCCATGATCGCTCTGCTCTGCCTTTTTGGCGGGGTCAGCATTGCATCCTGGAATGCG CTGGACGTGTTGACTGTTGAACTCTACCCCTCAGACAAGAGGACCACAGCTTTTGGCTTC CTGAATGCCCTGTGTAAGCTGGCAGCTGTGCTGGGGATCAGCATCTTCACATCCTTCGTG GGAATCACCAAGGCTGCACCCATCCTCTTTGCCTCAGCTGCCCTTGCCCTTGGCAGCTCT CTGGCCCTGAAGCTGCCTGAGACCCGGGGGCAGGTGCTGCAGTGA
- Chromosome Location
- 1
- Locus
- 1q21.2
- External Identifiers
Resource Link UniProtKB ID Q7L0J3 UniProtKB Entry Name SV2A_HUMAN GenBank Protein ID 40788343 GenBank Gene ID AB018279 GenAtlas ID SV2A HGNC ID HGNC:20566 - General References
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