Reaction: Naproxen to 1 product

Reaction
Naproxen
DB00788
    Naproxen O-glucuronide
    DBMET00160
    Reaction type
    glucuronidation
    Direction
    Major circulating metabolite?
    Yes
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Bowalgaha K, Elliot DJ, Mackenzie PI, Knights KM, Swedmark S, Miners JO: S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen. Br J Clin Pharmacol. 2005 Oct;60(4):423-33. doi: 10.1111/j.1365-2125.2005.02446.x. [Article]
    Comments
    Not Available
    Enzymes
    Not Available