Reaction: Florbetapir F-18 to 1 product

Reaction
Florbetapir F-18
DB09149
    [18F]AV-160 (desmethyl-[18F]AV-45)
    DBMET01426
    Reaction type
    demethylation
    Direction
    Not Available
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, Dannals RF, Nandi A, Brasic JR, Ye W, Hilton J, Lyketsos C, Kung HF, Joshi AD, Skovronsky DM, Pontecorvo MJ: In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). J Nucl Med. 2010 Jun;51(6):913-20. doi: 10.2967/jnumed.109.069088. [Article]
    2. Choi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, Benedum TE, Kilbourn MR, Skovronsky D, Kung HF: Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain. J Nucl Med. 2009 Nov;50(11):1887-94. doi: 10.2967/jnumed.109.065284. Epub 2009 Oct 16. [Article]
    Comments
    Not Available
    Enzymes
    Not Available